16 results
diagnosis management differential hematology syndrome nephrology testing vasculitis apml approach classification cppd differentiation disease druginduced gap globulin hyperkalemia joint k
Approach to Gout Diagnosis: r/o septic arthritis! Needle-shaped, negative birefringent crystals Treatment: • Weight loss, diet, d/c culprit
Approach to Gout ... Diagnosis: r/o septic arthritis ... flares/year 2) Gouty ... Urate nephropathy, renal ... #ULT #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Lyme), reactive arthritis ... , gout or pseudogout ... Parallel, yellow = gout ... Joint #Pain #MSK #rheumatology ... #approach #workup
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Renal Syndromes ... erythematosus, Rheumatoid arthritis ... Investigations • Labs: CBC ... confirm DAH, rule out
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
resulting in an acute arthritic ... Acute CPP Crystal Arthritis ... Synovial Fluid: • WBCs ... Fluid Testing: • WBCs ... #Comparison #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... mononeuritis multiplex WORKUP ... coagulopathy) • CBC ... gross hematuria, RBC ... diagnosis #management #treatment
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
calcinosis • Pulmonary ... arterial HTN) • Renal ... : scleroderma renal ... Scleroderma #SSc #rheumatology ... symptoms #testing #workup
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... if high risk if WBC ... Imaging: CXR- pulmonary ... Anaphylaxis, Acute Renal ... Failure Treatment
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... synovial fluid • Gout ... urate crystals (gout ... #laboratory #workup ... diagnosis #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
and renal abnormalities ... Vessels: Supply gut ... Lab Tests: • CBC ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
post-hypothermia • ↓ Renal ... Excretion: - Renal ... reabsorption) Workup ... draw, ↑↑Plts or ↑↑WBC ... 15 suggests ↓ renal
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