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anemia hemolytic oncology algorithm atlas workup bloodcell cerebritis classification cns cold elevatedmcv erythematosus extravascular hodgkins intravascular key lupus lymphoma macrocytic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
. primary cold agglutin ... disorders, Mycoplasma ... • Intrinsic RBC ... #differential # ... diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Syndrome (CAS): ... Diagnosis: • hemolytic ... smear - RBC agglutination ... #disease #hemolytic ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
other reproducible morphologic ... hypertension • Unusual RBC ... acanthocytes - Consider RBC ... membrane disorder ... #workup #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... RBC) Morphology ... Unstable hemoglobin disorders ... #Morphology #differential ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... coagulopathy (DIC) #RBC ... #key #diagnosis ... hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Normal Blood Smear ... Neutrophils - Low RBC ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... (CVID, WAS), (neurologic ... ), HBsAg/anti-HBc ... Diagnosis #Causes ... #Workup #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... +Organomegaly+↑RBC ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Rare Disorder: ... Causes: - Idiopathic ... - CBC may also ... #diagnosis #dermatology
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