32 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... prevention (statin for CVA ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
- Diagnosis and ... thrombocythemia), Autoimmune ... #Diagnosis #Management ... #treatment #hematology ... #differential
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
and treatment can ... Inflammatory causes ... • Systemic lupus ... #neurology #inflammatory ... #differential #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... usually IgG) (e.g. lupus ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Atypical HUS, autoimmune ... S - Systemic Lupus ... #differential # ... hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
↑ LDH • Anti-RBC ... • Blood smear: Differential ... 2) LOOK FOR a cause ... #management #treatment ... #rheumatology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Metabolic • Renal ... Neoplastic / Hematologic ... Hepatitis • HIV Autoimmune ... • Somatization Disorder ... Chronic Fatigue Syndrome
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential ... hypertension and/or drug treatment ... - Autoimmune disorders ... #diagnosis #causes ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... disease • Non-autoimmune ... rheumatologic diseases ... APLA/LAC: • Renal ... #Rheumatology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
and Management ... Hyperthyroidism - Autoimmune ... #Diagnosis #Management ... #causes #treatment ... #nephrology