41 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
• Myopathy (Also ... Erythematosus #SLE #MSK ... #pathophysiology ... #signs #symptoms ... #diagnosis
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... : - Catch-all term ... Ill-appearing, vital sign ... Immunocompromised #Diagnosis ... Targetoid #Algorithm #Differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... lateral sclerosis Pathophysiology ... conditions listed in differential ... Treatment: - Multidisciplinary ... Lateral #Sclerosis #neurology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... / Symptoms / Complications ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
/ Symptoms / Complications ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms ... #signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , AKI, acute limb ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Diagnosis Framework ... 5X ULN • AST/ALT ... AST declines > ALT ... HAGMA • Late complication ... #nephrology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
syndromes such as ... Multiple Sclerosis Treatment ... objective evidence of neurologic ... #management #neurology ... #treatment #MS
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
generally defined as ... • Treatment includes ... Kathryn Watson @ ... #Vancomycin #AKI ... pharmacology #toxicology #diagnosis
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Kidney Injury (AKI ... ) What to ask ... uric acid (rhabdo/TLS ... #Nephrology #Diagnosis ... Algorithm #Causes #Differential