10 results
Acetaminophen toxicity
Emergency Department Workup and Management - Rumack Matthew Nomogram

#Diagnosis #Management #Toxicology #APAP #Acetaminophen #Rumack #Nomogram
Acetaminophen toxicity ... #Diagnosis #Management ... #Toxicology #APAP ... Rumack #Nomogram #Stages ... #Toxicity #Overdose
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
life-threatening toxicity ... Kathryn Watson @ ... #ILE #Therapy #Toxicology ... #Management #Pharmacology ... #Overdose #intralipid
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
hydroxybutyrate (GHB) - Toxicology ... of GHB toxicity ... Kathryn Watson @ ... #Toxicity #Diagnosis ... #Management #Pharmacology
Stages of Iron Toxicity

Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
Stages of Iron Toxicity ... Iron overdose ... Recovery from GI symptoms ... #Iron #Toxicity ... #Toxicology #Diagnosis
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
also includes symptoms ... altered mental status ... Kathryn Watson @ ... #Toxicology #Diagnosis ... #Management
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
described phases of toxicity ... post-ingestion) - Symptom ... Kathryn Watson @ ... #Toxicology #Diagnosis ... #Management #Ferrous
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Neurological symptoms ... Medication/Drug toxicity ... Syndrome #diagnosis #management ... #neurology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
gradually with symptoms ... macrophages in alveolar spaces ... Improvement in symptoms ... Pulmonary #diagnosis #management ... #Toxicology
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... the most severe overdoses ... evidence of marrow toxicity ... Kathryn Watson @ ... #Toxicity #Management
Digoxin Pharmacology and Monitoring

 • Digoxin’s half-life is 30-45 hours in healthy adults
 • When monitoring
altered mental status ... Kathryn Watson @ ... Pharmacology #Monitoring #toxicology ... #management #toxicity