10 results
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
and Differential Diagnosis ... risk factors (eg ... hypertension (eg ... and metabolic alkalosis ... hypertension (eg
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
WBC >100k, + lab signs ... hydration - Hyperkalemia ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... heparinized tube) • ECG ... Ca-gluconate or 1g CaCl ... #Diagnosis #Management ... #nephrology #K
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Evaluation and Management of Hypokalemia

Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
search for warning signs ... warranting urgent treatment ... electrocardiography (ECG ... #Diagnosis #Hypokalemia ... #Evaluation #Algorithm
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... Treatment of GCA
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... Signs of congestion ... ECG is vital while ... patient causing hypovolemia ... #algorithm #management
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
• Thrombosis (e.g ... ET-associated mutation (e.g ... thrombocytosis (e.g ... • Treatment algorithms ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g ... #Management #Hematology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Treatment Overview ... liver insult (e.g ... evaluation essential in all ... Hepatorenal #Syndrome #Hepatology ... #Nephrology #Diagnosis