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diagnosis differential hepatology management algorithm secondary systemic anemia generalized hepatopulmonary oncology pruritus rheumatology aclf acute albumin aplastic arterial cellulitis chemistry
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... months without treatment ... Injury (DILI) ... #Cirrhosis #Hepatology
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Nonalcoholic fatty liver ... heart failure (chronic ... disease (Budd-Chiari syndrome ... #Differential #Hepatology ... #Cirrhosis #Causes
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 Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... • Acute kidney injury ... • Hepatorenal syndrome ... Indications #Management #Cirrhosis ... #treatment #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... hepatitis: < 1 • Cirrhosis ... : > 3 • Chronic
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... dechallenge • Acute or chronic ... e.g. ascites), Chronic ... #Algorithm #hepatology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
discoloration) • Liver ... cirrhosis • Congestive ... discoloration) • Chronic ... • Nephrotic syndrome ... Systemic #Secondary #dermatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Systemic and Primary Causes ... • Cholestatic liver ... Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... #generalized #dermatology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
cirrhosis, chronic ... cirrhosis, chronic ... Kidney stones caused ... cirrhosis, chronic ... Tolvaptan) • Treatment
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
• Anemia of chronic ... : Alcohol use, Liver ... Myelodysplastic syndrome ... differential #diagnosis #causes ... #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
> 2 • NASH, Chronic ... hepatitis: < 1 • Cirrhosis ... : > 3 • Chronic ... • Gilbert's syndrome ... #differential #Hepatology
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