12 results
Summary table of mechanism of action, side effect and contraindications of commonly used diabetic drugs. 

#pharmacology
mechanism of action, side ... #pharmacology #dm2
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... disease Common Side ... Toxicities: • GI side ... #Metformin #Pharmacology ... #Summary #DM2 #
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... in CKD Common Side ... Sulfonylureas #Pharmacology ... #Summary #DM2 #
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... mL/minute/1.73 m2 ... of use) Common Side ... SGLT2 #Inhibitors #Pharmacology ... #Summary #DM2 #
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... pancreatitis Common Side ... Toxicities: • Gl side ... Receptor #Agonists #Pharmacology ... #Summary #DM2 #
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
drugs include side ... Side effects include ... SGLT2 #Inhibitors #Pharmacology ... #Medications #DM2
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... failure Common Side ... DPP4 #Inhibitors #Pharmacology ... #Summary #DM2 #
Third Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) Example: Aripiprazole
Dopamine D2 Receptor Partial Agonist
 • Binds
Mechanisms and Side ... Aripiprazole Dopamine D2 ... • Binds to the D2 ... to bind to the D2 ... #SideEffects #pharmacology
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Mechanisms and Side ... therapeutic and side ... • Dopamine D2 ... action of DA on D2 ... #SideEffects #pharmacology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
with only few side ... Renal #Dosing #Pharmacology ... Management #Diabetes #DM2