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differential arterial coagulation management thrombosis vasculitis venous abnormal aptt classification clots cryofibrinogenemia dic disseminated embolism infarction intravascular pathophysiology polychondritis prolonged
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... atheroemboli) • Aorta ... thrombus - atrial ... coagulation and other causes ... pathophysiology #hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... - Differential Diagnosis ... Popliteal artery aneurysm ... : Causes arterial ... #clots #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Prolonged Activated Partial ... drugs e.g. direct thrombin ... #diagnosis #differential ... #hematology #coagulation
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
emboli, and ocular thrombi ... Cryofibrinogenemia Diagnosis ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... < 30 years - Aorta ... aneurysms can also ... aortitis, aortic aneurysm ... #rheumatology #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Increased thrombin ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Causes of Renal Infarction - Differential Diagnosis Thrombosis: Spontaneous • Atherosclerotic disease of aorta and renal artery
Causes of Renal ... - Differential Diagnosis ... renal artery • Aneurysms ... infarction with mural thrombi ... : Left atrial myxoma
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
< 30 years • Aorta ... Arteritis): • Aorta ... tract, and often causes ... aneurysms can also ... #Rheumatology
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Large vessels (aorta ... other large vessel aneurysms ... /EGPA • RA Diagnosis ... Polychondritis #rheumatology ... #diagnosis #management
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