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diagnosis oncology differentiation emergencies excretion hematology hemeonc management medications nephrology oncologic pharmacology renal table
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Diuretics and Agents ... Symport (Loop Diuretics ... ; High-Ceiling Diuretics ... pulmonary edema ... Tolvaptan) • Treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... • Steroids: IV ... Supportive Care: Diuresis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
fever: - Fever + ANC ... Adjuncts: loop diuretics ... : - Seen with AML ... (~20 %) and APL ... renal failure, pulmonary
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