18 results
ANCA-Associated Vasculitis
A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (GPA ... polyangiitis (MPA ... polyangiitis (EGPA ... vasculitis - MPO ... #CANCA #PANCA #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
-ANCA (C-ANCA): ... GPA >>> MPA > eGPA ... • MPO-ANCA (P-ANCA ... ): eGPA, MPA >>> ... GPA Stanford Internal
Frequency of ANCA Positivity in Different Conditions
ANCA-Associated Vasculitis
 • GPA - PR3-ANCA 75%, MPO-ANCA 20%, 5%
GPA - PR3-ANCA 75% ... , MPO-ANCA 20%, ... • MPA - PR3-ANCA ... • EGPA - PR3- ... ANCA 5%, MPO-ANCA
ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis

MPA → usually p-ANCA
GPA → usually c-ANCA
EGPA →
Differential Diagnosis MPA ... GPA → usually ... c-ANCA EGPAANCA ... (MPO) C-ANCA ( ... PR3) X-ANCA (elastase
ANCA Vasculitis - GPA, MPA, Eosinophilic GPA

doi:10.1038/s41572-020-0204-y

#ANCA #Vasculitis #GPA #MPA #Eosinophilic #rheumatology #diagnosis #comparison #table
ANCA Vasculitis ... - GPA, MPA, Eosinophilic ... GPA doi:10.1038 ... #Vasculitis #GPA ... #MPA #Eosinophilic
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (GPA ... Polyangiitis (MPA ... ) - ANCA Vasculitis ... #Polyangiitis #GPA ... #ANCA #Vasculitis
2021 ACR/VF Guidelines for Management of Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA)

#Granulomatosis #Polyangiitis #GPA
Polyangiitis (GPA ... Polyangiitis (MPA ... #Polyangiitis #GPA ... #Polyangiitis #MPA ... algorithm #vasculitis
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management
 • Giant Cell Arteritis (GCA)
 •
Vasculitis Management ... Polyangiitis (GPA ... Polyangiitis (MPA ... Polyangiitis (EGPA ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
myeloperoxidase (MPO-ANCA ... > PR3 60% • GPA ... 100 % Commonly MPO-ANCA ... Vasculitis: + MPO-ANCA ... (Dx: GPA, EGPA,
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
>PR3 - ANCA+ 90% ... >MPO - ANCA+ 60% ... >PR3 - ANCA+ 30- ... disease - MPO>PR3 ... antibodies #diagnosis #rheumatology