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rheumatology differential hematology lupus management monoclonal signs sle symptoms bee behcet classification criteria disease eularacr gammopathy manifestations mgus neuromyelitis nmo
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... , macular, patchy ... Differential Diagnosis ... Clinical Features ... artery or vein
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... desaturation, Scotoma, Ocular ... lupus erythematosus ... Manifestations #diagnosis ... #neurology #symptoms
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... - Differential Diagnosis ... Neurologic-Centered ... capillary leak syndrome ... #hematology #oncology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Lupus Erythematosus ... Clinical Domains ... least 2 joints • Neurologic ... #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Hypergammaglobulinemic macular ... , retinal, DVT, ... #Differential #Diagnosis ... #Oncology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
central nervous system ... • Genetic • Retinal ... MRI lesions and clinical ... consistent with MS ... #neurology #noninflammatory
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... association • M > F Clinical ... ulceration • Ocular ... skin injury) • Neurologic ... (Clinical Dx).
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... pulmonary and renal ... affects the skin, neurologic ... ischemia • Skin: Erythematous ... cognitive impairment, neurologic
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... gland) biopsy • Ocular ... salivary ducts Clinical ... Central nervous system ... phenomenon (16%) MSK
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