118 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... suspect underlying hematologic ... disorders • Diagnosis ... #HES #Hematology ... #eosinophils #diagnosis
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Systemic Sclerosis ... distal to elbows/wrists ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... SLE), Sjogren's Syndrome ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Abnormal Coagulation Tests ... Prolonged aPTT and ... APTT #Laboratory #Hematology ... #Diagnosis #Workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Kawasaki, Nephrotic syndrome ... Acute bacterial and ... #Algorithm #hematology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Antinuclear (ANA ... Initial screening test ... block • Sjogren syndrome ... #SLE #Summary #diagnosis ... #rheumatology #
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
the Evaluation and ... Sickle Cell Crises Clinical ... Management #Diagnosis ... #Management #Hematology ... Manifestations #Workup
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ANA ... • Scleroderma (Systemic ... Autoantibodies #Rheumatology ... #diagnosis #associations
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Differential #Causes #Workup ... #Hematology #Diagnosis ... GrepMed Recommended Text