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diagnosis barre differential disease hematology treatment als amyotrophic apml behcet calcium cauda caudaequina causes cerebritis cns comatose cppd criteria deposition
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... • Pain: Due to nerve ... #diagnosis #management ... #treatment #neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome Features Required for Guillain-Barré Syndrome: • Progressive muscle weakness
Diagnostic Criteria for Guillain ... Features Required for Guillain-Barré ... , Mild sensory symptoms ... signs, Cranial nerve ... diagnosis #criteria #neurology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... the underlying pathophysiology ... #diagnosis #management ... #neurology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... TLS #diagnosis #management ... #hematology
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
compression of nerve ... spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... Tethered cord • Guillain-Barre ... diagnosis #causes #neurology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... APML #diagnosis #management ... #hematology #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Neurological symptoms ... #diagnosis #management ... #neurology
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
Unresponsive wakefulness syndrome ... • Locked-in syndrome ... • Mutism Pathophysiology ... threat Cranial Nerves ... #PhysicalExam #neurology
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