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diagnosis differential anca acr2021 granulomatosis management polyangiitis classification cutaneous guidelines microscopic rash skin treatment ana antibodies antibody anticoagulation antineutrophil antinuclear
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
ANCA (C-ANCA): GPA ... >>> MPA > eGPA ... ): eGPA, MPA >>> ... GPA Stanford Internal ... #rheumatology
ANCA Vasculitis - GPA, MPA, Eosinophilic GPA doi:10.1038/s41572-020-0204-y #ANCA #Vasculitis #GPA #MPA #Eosinophilic #rheumatology #diagnosis #comparison #table
ANCA Vasculitis ... - GPA, MPA, Eosinophilic ... GPA doi:10.1038 ... #GPA #MPA #Eosinophilic ... #rheumatology #
2021 ACR/VF Guidelines for Management of Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) #Granulomatosis #Polyangiitis #GPA
Polyangiitis (GPA ... Polyangiitis (MPA ... #Polyangiitis #GPA ... ACR2021 #Management #rheumatology ... #algorithm #vasculitis
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management • Giant Cell Arteritis (GCA) •
Cell Arteritis (GCA ... Polyangiitis (GPA ... Polyangiitis (MPA ... Sources: GCA ... #rheumatology
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
polyangiitis (GPA ... polyangiitis (MPA ... vasculitis - MPO ... - MPO > PR3 ... #Rheumatology
Frequency of ANCA Positivity in Different Conditions ANCA-Associated Vasculitis • GPA - PR3-ANCA 75%, MPO-ANCA 20%, 5%
• GPA - PR3-ANCA ... 75%, MPO-ANCA 20% ... ANCA negative • MPA ... MPO-ANCA 80%, 10% ... #rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Polyangiitis (GPA ... Polyangiitis (MPA ... #Polyangiitis #GPA ... #Polyangiitis #MPA ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
> PR3 60% • GPA ... and branches • GCA ... purpura: strong sign ... • ANCA (Dx: GPA ... differential #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- GPA - EGPA ... - MPA • CTD ... Differential #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... (80-90%) > MPO ... >MPO - ANCA+ 60% ... - MPO: 75-80% - ... antibodies #diagnosis #rheumatology
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