38 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
distal to elbows/wrists ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing ... #workup
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Treatment: • ... Hydroxychloroquine *Short ... #SLE #Summary #diagnosis ... #rheumatology #
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
central nervous system ... important, as early diagnosis ... and treatment can ... BEE #Syndromes #neurology ... #differential #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Cerebrovascular Disease ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... Immune Complex: Systemic ... testing: anti-ANCA ... #differential #diagnosis ... #nephrology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
and Workup Blood ... Work: - Hypokalemia ... dominant kidney disease ... kidneys Genetic Testing ... #Workup #nephrology
Causes of Bradykinetic Movement Disorders - Differential Diagnosis Algorithm
Parkinson's Disease (TRAP):
• Resting Tremor
• Cogwheel Rigidity
• Akinesia/Bradykinesia
•
- Differential Diagnosis ... Algorithm Parkinson's Disease ... (TRAP): • Resting ... backwards Multiple System ... MovementDisorders #Neurology
Causes of Tremors - Movement Disorders - Differential Diagnosis Algorithm
Action Tremor - Occurs During Voluntary Muscle
- Differential Diagnosis ... multiple sclerosis) Resting ... palsy • Multiple System ... MovementDisorders #Neurology ... #Differential #Diagnosis
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
suspicion of severe disease ... guidelines General - Systemic ... splenomegaly, abnormal neurology ... Rheumatology ... Peds #Pediatrics #Diagnosis