27 results
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
in macrophages Diagnosis ... in GBA1 gene Clinical ... Yann Nguyen @YannNgyn ... Gauchers #Disease #Diagnosis ... #Signs #Symptoms
Obstetric patients often pose challenges to anesthesiologists, as lab values and parameters vary from a non-pregnant
anesthesiologists, as lab values ... vary from a non-pregnant ... physiologic changes in pregnant ... patient data or clinical ... #diagnosis #clinical
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... : • Disease fatal ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... : • Defect in fetal ... ) Differential Diagnosis ... Maternal Support - Critical ... #Fatty #Liver #Pregnancy
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Pathogenesis and clinical ... vara • Coxa valga ... Joint Pain • Valgus ... causes #symptoms #signs ... #diagnosis #msk
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
Clinical manifestations ... abdominal pain and fecal ... #anaphylaxis #signs ... #symptoms #diagnosis
Multiple Myeloma Diagnosis and Management Summary
Clinical Signs:
 • hyperCalcemia 28% (bone demineralization)
 • Renal disease 48%
Multiple Myeloma Diagnosis ... Management Summary Clinical ... Signs: • hyperCalcemia ... pathologic fx) Diagnosis ... ratio >100 if FLC value
Woltman’s sign on Physical Exam

53-year-old man presented with fatigue and sensitivity to cold. A physical examination
Woltman’s sign on ... evaluation confirmed a diagnosis ... Woltman’s sign, ... associated with pregnancy ... Reflexes #Delayed #Clinical
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism
 • Low TSH, Low normal T4
resolution of pregnancy ... , critical illness ... Hyperthyroidism → Signs ... Hyperthyroidism #algorithm #diagnosis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... >10 mmHg - clinically ... significant portal HTN Signs ... Fatty liver of pregnancy ... #Differential #Diagnosis