7 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
- TTP/HUS, HELLP ... Syndrome and Acute ... Three syndromes ... coagulation defects. 1) HELLP ... AFLP #obstetrics #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... : • Defect in fetal ... Preeclampsia, HELLP ... #Pregnancy #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
, no necrosis HELLP ... Syndrome (Hemolysis ... and hemorrhage Acute ... #hepatology #obstetrics ... diagnosis #icp #HELLP
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... presents as an acute ... or subacute febrile ... management #treatment #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... PBC, PSC, IgG4, HLH ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... diagnosis #algorithm #hepatology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
(Acute Febrile ... Abnormal laboratory values ... #Acute #Febrile ... Criteria #Diagnosis #Hematology ... #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... consideration in febrile ... • Prognosis: Fatal ... - Elevated liver ... Diagnosis #Management #Hematology