6 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... features in most cases ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Hyperviscosity, TTP, APLS ... Intravenous Drug Use • Pregnancy ... from prosthetic valves ... Antiphospholipid antibodies (APLS ... coagulation and other causes
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Not all MAHAs are ... TMAs cause MAHA ... (catastrophic APS ... transplant, infection, pregnancy ... Microangiopathy #TMAs #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... : • Defect in fetal ... = nonspecific (nausea ... , ↑Tbili/Dbili/AP ... #hepatology #obstetrics
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
high index of clinical ... Autoimmune (SLE/APLS ... Hypercoagulable states • Clinical ... left-sided heart valves ... in up to 30% of cases
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Antiphospholipid Syndrome (APLS ... - 1 or more clinical ... • Unexplained pregnancy ... maternal chromosomal causes ... ARUPConsult @ARUPLabs #APLS