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differential liver algorithm hematology hepatitis lfts management biliary cirrhosis obstetrics pathophysiology pbc primary syndrome acute ah alcoholic bandemia causes cbc
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... (AFLP) • Onset ... #Pregnancy #hepatology ... #differential #diagnosis ... #icp #HELLP #AFLP
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... : • Defect in fetal ... #hepatology #obstetrics ... #obgyn #diagnosis
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
of autoimmune disease ... pruritus after pregnancy ... 2/3 criteria are ... Elevated ALP 2. ... #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Wilson's • Pregnancy ... - AFLP, HELLP ... • Cholestatic disease ... US — Normal Bile ... Others #LFTs #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... melanoma, myeloma • Pregnancy ... function may be abnormal ... #differential #diagnosis ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... of cholestatic disease ... Alcoholic liver disease ... liver #chemistry #diagnosis ... #differential #Hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
metabolic syndrome criteria ... ALP, alkaline phosphatase ... alcohol-related liver disease ... non-alcoholic fatty liver disease ... #Algorithm #Hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
but elevated as disease ... obstruction • ALP ... cholestasis of pregnancy ... , Cardiac diseases ... #workup #hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
Clinical diagnosis ... >1.5, and both values ... #diagnosis #Alcoholic ... Hepatitis #AH #hepatology ... #criteria
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Diagnostic Criteria ... inflammatory disease ... , or pregnancy or ... Abnormal laboratory ... #Diagnosis #Hematology
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