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diagnosis algorithm causes aflp ascites management obstetrics pathophysiology saag abnormal albumin arterial chemistry comparison dili drug embolism enzymes gastroenterology gradient
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... : • Defect in fetal ... infiltration) Differential ... #Liver #Pregnancy ... #hepatology #obstetrics
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... Liver of Pregnancy ... #Disease #Pregnancy ... #hepatology #obstetrics ... hepatitis #comparison #differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Wilson's • Pregnancy ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... - Acute fatty ... liver of pregnancy ... Causes #diagnosis #differential ... #hepatology #SAAG
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... metastasis • Fatty ... liver of pregnancy ... Diagnosis #causes #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
non-alcoholic fatty ... liver disease; ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential #
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum ... disease: > 2 ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Gradient (SAAG) - Differential ... ascites - Massive liver ... - Acute fatty ... liver of pregnancy ... #Diagnosis #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Myeloproliferative disease ... Intravenous Drug Use • Pregnancy ... Syndrome, Ischemic Liver ... #differential #
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