13 results
diagnosis algorithm injury causes hepatitis transaminitis abnormal aflp hematology management obstetrics pathophysiology acute arterial chemistry comparison dili drug elevated embolism
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Wilson's • Pregnancy ... - AFLP, HELLP ... • Cholestatic disease ... • Others #LFTs
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... , no necrosis HELLP ... #Disease #Pregnancy ... #hepatology #obstetrics ... hepatitis #comparison #differential
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hemochromatosis, Wilson's disease ... NAFLD, Autoimmune, HELLP ... , Celiac disease ... #Diagnosis #hepatology ... Transaminitis #LFTs
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... : • Defect in fetal ... infiltration) Differential ... Preeclampsia, HELLP ... #Pregnancy #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Injury - Differential ... biliary obstruction, HELLP ... Toxic: Medication, Pregnancy ... #Injury #Differential ... Acute #algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... AIH, Wilsons, Pregnancy ... - AFLP, HELLP ... Burak @kwburak #LFTs
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... TTP, HUS, DIC, HELLP ... - Grafts, Valves ... Defects, Drugs, Liver ... Disease, PNH
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum ... disease: > 2 ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... melanoma, myeloma • Pregnancy ... : HELLP • Iatrogenic ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
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