15 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP Syndrome and Acute ... Fatty Liver of Pregnancy ... (AFLP) Three syndromes ... TTPHUS #HELLP #AFLP ... obstetrics #hematology #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... : • Defect in fetal ... headache, malaise) → Acute ... iMedEducation #AFLP
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in Pregnancy ... and hemorrhage Acute ... (AFLP) • Onset ... #differential #diagnosis ... #icp #HELLP #AFLP
Antenatal / Prenatal Care Schedule 
At Every Visit: Weight, Blood pressure, Psychosocial screening, Counseling re. Indications
-28 weeks): • Fetal ... serum screen (AFP ... • ± Prenatal diagnosis ... - Chorionic villus ... Care #Schedule #Diagnosis
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Biliary Cirrhosis - Diagnosis ... pruritus after pregnancy ... Diagnose PBC if ... 2/3 criteria are ... Elevated ALP 2.
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Hepatocellular - Check Acute ... Mixed - Check Acute ... Imperative to Identify Acute ... liver #chemistry #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Vascular Causes of Acute ... melanoma, myeloma • Pregnancy ... #differential #diagnosis
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Encephalopathy - Acute ... ) Deficiency - Diagnosis ... and Management Diagnosis ... - Caine Criteria ... Hyperemesis of pregnancy
Approach to Possible Hypertensive Emergency

criteria required to diagnose hypertensive emergency
(1) Severe hypertension
 - Usually a MAP
Hypertensive Emergency criteria ... required to diagnose ... patients who have acute ... hypertension (e.g. pregnant ... , such as: - Acute
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... Sweet Syndrome (Acute ... inflammatory disease, or pregnancy ... Abnormal laboratory values ... Sweet #Syndrome #Acute