13 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
or AST > ALP): ... AIH, Wilsons, Pregnancy ... - AFLP, HELLP ... - CBD stone, Biliary ... #hepatology #LiverFunctionTests
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
for the liver ALP ... - Biliary tree ... Transaminase, ALP ... ) / (ALP / ULN ALP ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... : • Defect in fetal ... iMedEducation #AFLP ... #hepatology #obstetrics
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP Syndrome and Acute ... (AFLP) Three syndromes ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... #diagnosis #table
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... pruritus after pregnancy ... 2/3 criteria are ... Elevated ALP 2. ... #Algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... Algorithm ALP ... - Increased ALP ... - Drugs - Pregnancy ... #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... • Wilson's • Pregnancy ... - AFLP, HELLP ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... melanoma, myeloma • Pregnancy ... disease - If ALP ... both are normal, ALP ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... /ULN ALP) • R ... GGT/5-NT: ↑ • ALP ... liver #chemistry #diagnosis ... #differential #Hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
and hemorrhage Acute ... (AFLP) • Onset ... #hepatology #obstetrics ... #differential #diagnosis ... #icp #HELLP #AFLP