11 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... #Workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... (usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... differential #diagnosis #hematology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... • Anemia • ... Pulmonary Disease Neurologic ... • Drug Abuse (e.g
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... specifically immune thrombocytopenia ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Causes of Neutropenia ... cause - Maternal ... Constitutional disorders, eg ... Megaloblastic anemia-rare ... #hematology
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
result in permanent neurologic ... - Infection (e.g ... syphilis, and HIV ... (more commonly ... (more commonly
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
definition: Most common ... with systemic, neurologic ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... systemic complaints- anemia
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
in recipient (e.g ... Causes purpura & ... severe thrombocytopenia ... Extremely rare - HIV ... diagnosis #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g ... Diagnosis #Management #Hematology