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diagnosis differential management algorithm rheumatology anemia neurology oncology aplastic bleeding blood bruising cardiology castleman cerebritis chronic classification cns cryoglobulinemia cryoglobulins
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... and Platelet Disorders ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Toxic Damage (e.g ... Displacement (e.g ... Foreign Surface (e.g ... #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Diagnosis Algorithm Thrombocytopenia ... Sequestration Disordered ... Rare • Drugs (e.g ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... lymphoproliferative disorders ... deficiencies (e.g ... differential #diagnosis #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... for secondary causes ... glucocorticoid treatment ... signs or symptoms (eg ... Differential #diagnosis #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Hepatitis • HIV ... • Drug Abuse (e.g ... • Somatization Disorder
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Headache, Movement disorders ... , Seizure disorders ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Treatment:
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
of information (e.g ... non-essential drug/HDS treatments ... for alternative causes ... Hepatic vascular disorder ... (e.g. ascites),
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... HBV infection, HIV ... (e.g. systemic ... classification #rheumatology
Causes of ST Segment Elevation - Differential Diagnosis Framework STEMI: • Upsloping convex STE: "Pardee's sign" +
Causes of ST Segment ... Diagnosis Framework STEMI ... Electrolyte Disorders ... diagnosis #cardiology #ecg ... #ekg #electrocardiogram
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