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diagnosis differential rheumatology management algorithm primarycare arterial atlas autoimmune basics blood bruising cerebritis classification cns common comparison cryofibrinogenemia cryoglobulinemia cryoglobulins
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Sequestration Disordered ... Rare • Drugs (e.g ... Connective Tissue Disorders ... #Hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... for secondary causes ... signs or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Epidemiology: young ... Immunosuppression (e.g ... Autoimmune diseases (e.g ... Malignancies (eg ... #differential #hematology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... altered colour e.g ... bruise') is where bleeding ... a generalized disorder ... #Diagnosis #Dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
, Seizure disorders ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... inflammation, leading ... Lumbar Puncture, EEG
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... (e.g. systemic
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Drug history, e.g ... and skin haemorrhage ... connective tissue, e.g ... #Bleeding #Disorders ... pediatrics #diagnosis #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hematological: - HIT ... Testosterone - Coumadin skin ... thrombosis in young ... Venous #Arterial #pathophysiology ... #hematology #differential
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... Paradoxical spontaneous bleeding ... cryoglobulinemia Associated Disorders ... cryoglobulins • Negative causes ... #hematology
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