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diagnosis differential management rheumatology syndrome algorithm barre guillain treatment acidosis blood cerebritis chronic classification cns conditions crisis disorders elevation erythematosus
Hypoxia and Hypoxemia - Overview Hypoxia - insufficient oxygen delivered to tissues to meet demands Hypoxemia - low
(e.g low cardiac ... carrying capacity (e.g ... cannot use oxygen (e.g ... #diagnosis #causes ... #pathophysiology
Hypoxemic Respiratory Failure - Differential Diagnosis Framework DECREASED INSPIRED OXYGEN • Low PATM Can decrease first part
High altitude (eg ... respiratory drive due to neurologic ... direction leads to hypoxemia ... Intrapulmonary shunting (eg ... intracardiac shunting (eg
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Risks factor for HIV ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... or if a primary hematologic ... #Workup #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Chronic Obstructive Pulmonary ... Disease Neurologic ... • Drug Abuse (e.g
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Polycythemia - Acquired Causes ... : • Hypoxia-driven ... : Cardiac/pulmonary ... Paraneoplastic (e.g ... Diagnosis #Algorithm #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... coma - Pulm: Hypoxia ... unless worrisome EKG ... diagnosis #management #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
usually: - hypoxemia ... by excretion (e.g ... its metabolism (e.g ... output - Acute pulmonary ... Ethylene glycol - HIV
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Wilson's disease Pulmonary ... Spondyloarthropathies, SLE • Pulmonary ... syndrome - SLE Neurologic ... disease, Vasculitis (e.g ... differential #diagnosis #rheumatology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Campylobacter jejuni - HIV ... Electrodiagnostic studies - EMG ... management #treatment #neurology
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