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diagnosis management differential neurology hematology algorithm barre guillain bee cerebritis classification clinical cns criticalcare cryofibrinogenemia cryoglobulinemia cryoglobulins encephalopathy endocarditis erythematosus
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... methotrexate) • Drugs Autoimmune ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... : • Pathophysiology ... unless worrisome EKG ... diagnosis #management #hematology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... an underlying autoimmune ... diagnosis and treatment ... pachymeningitis • HIV ... skull neoplasms (e.g
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Campylobacter jejuni - HIV ... Electrodiagnostic studies - EMG ... Treatment: • Plasmapheresis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Pathophysiology ... the result of an autoimmune ... unit activity on EMG ... of diazepam • EMG ... TPO, TTG, etc EMG
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... HBV infection, HIV ... tissue disorder (e.g ... classification #rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
/Sepsis/Shock, Autoimmune ... Etiology: • Pathophysiology ... • EEG: With persistent ... the underlying cause ... • Treatment of
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Constitutional disorders, eg ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... #hematology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology ... and cauda equina TREATMENT
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