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diagnosis management differential algorithm syndrome oncology neurology anemia classification hepatology thrombocytopenia comparison dermatology disorders guillain hemeonc hemophagocytic hlh hodgkins intravascular
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Vasculitis • Infection ... Foreign Surface (e.g ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Causes of Splenomegaly ... Diagnosis Algorithm Infectious ... • Thrombus (e.g ... Myeloproliferative disorders (eg ... #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Pseudotumor - Infectious ... • CMV • HIV ... Bites • Young ... #Hematology #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g ... ., HIV), EBV infection ... Autoimmune diseases (e.g ... Malignancies (eg ... #differential #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Pathophysiology ... response preceding infection ... Campylobacter jejuni - HIV ... Electrodiagnostic studies - EMG
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... • Malignancy Infectious ... Tuberculosis • Epstein-Barr ... • Drug Abuse (e.g
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
procedures - Infection ... Risks factor for HIV ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Causes of Isolated ... Antineoplastic Viral Infection ... • Epstein-Barr ... Childhood viruses • HIV ... #Hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm Infection • Bacterial • Abscess • Viral Medications
Causes of Neutrophilia ... Diagnosis Algorithm Infection ... Solid Tumour (e.g ... Diagnosis #Algorithm #Causes ... #Hematology
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