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diagnosis differential abnormal aflp aptt hellp inotropes obstetrics pharmacology pregnancy prolonged pt thrombocytopenia ttphus vasopressors algorithm anemia bleeding bruising complex
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Autoimmune disorders (e.g ... #comparison #diagnosis ... #hematology #deficiency
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Rare • Drugs (e.g ... • Vasculitis Coagulation ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... (usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... differential #diagnosis #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Nonspecific inhibitors e.g ... to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #differential #hematology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
presents with coagulation ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
presents with coagulation ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
(e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #differential #hematology ... #coagulation
Vasopressors Table Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Resistance, Main Uses ... /kg/min - Milrinone ... Vasopressors #Properties #Table ... Effect #Management #Comparison
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... Epidemiology: young ... Immunosuppression (e.g ... Autoimmune diseases (e.g ... Malignancies (eg
Common Vasopressors and Inotropes Norepinephrine (NE) - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
is not desired (e.g ... is not desired (e.g ... Bradyarrhythmias, Some cases ... Vasopressors #Inotropes #comparison ... #table #pharmacology
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