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Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
crises”. ... Serologic and EMG ... Gravis Treatment ... Crises - Severe ... diagnosis #management #neurology
Myasthenia Gravis - Summary • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
serologic, and EMG ... More likely to cause ... characteristic EMG ... glucocorticoids - can cause ... diagnosis #management #neurology
Classification of Diabetes Insipidus Central or neurogenic diabetes insipidus: - Congenital - Structural malformations affecting the hypothalamus
metastases, Infection (e.g ... (e.g., hypokalemia ... disease, Drugs (e.g ... Treatment is aimed ... Classification #Types #Nephrology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia Focal Hyporeflexia: • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... Hyporeflexia: • Hypercalcemia ... Deep coma (any cause ... polyneuropathy (e.g ... diagnosis #table #neurology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Liver Failure • Hypercalcemia ... Pulmonary Disease Neurologic ... Parkinson's • Myasthenia ... • Drug Abuse (e.g
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... malignant syndrome (e.g ... Phaeochromocytoma Neurologic
Pisa Syndrome (pleurothotonus) on Physical Exam A tonic flexion of the trunk of the body to one
Caused commonly ... by: - drugs (e.g ... neurodegenerative disorders (eg ... Treatment: anticholinergics ... PhysicalExam #clinical #neurology
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 Causes of Polyuria - Differential Diagnosis Excess Intake of Water: • Primary polydipsia (a.k.a. "psychogenic polydipsia") •
Causes of Polyuria ... SGLT2 inhibitors (e.g ... Hereditary, Lithium, Hypercalcemia ... Differential #Diagnosis #Causes ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... heparinized tube) • ECG ... only if no clear cause ... Terbutaline 7 µg/kg ... #potassium #nephrology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... brainstem syndromes (e.g ... AQP4-lgG disease; e.g ... Sjögren syndrome, Myasthenia ... Manifestations #diagnosis #neurology
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