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diagnosis algorithm management abnormal anemia cardiomyopathy coagulation disorders elevation peripartum prolonged pt thrombocytopenia treatment workup acidosis apml ascites bilirubinemia chf
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #hematology #coagulation
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #diagnosis #differential ... #hematology #coagulation
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework NCPE Pathophysiology: Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Edema - Differential ... Causes include: ... level <100 pg/ml EKG ... #edema #NCPE #differential ... #diagnosis #cardiology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Sepsis • Drugs (e.g ... • Gilbert's Syndrome ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Causes of Peripheral Edema - Differential Diagnosis Increased Hydrostatic Pressure • Volume Expansion: Kidney failure, Pregnancy, Medication
Edema - Differential ... Medication side effect (e.g ... Heart failure, Pulmonary ... Cirrhosis, Nephrotic syndrome ... • Filariasis (e.g
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... #hematology #secondary
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... #differential # ... diagnosis #hematology
Hypoxemic Respiratory Failure - Differential Diagnosis Framework DECREASED INSPIRED OXYGEN • Low PATM Can decrease first part
Respiratory Failure - Differential ... High altitude (eg ... edema (most common ... Intrapulmonary shunting (eg ... intracardiac shunting (eg
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