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diagnosis differential algorithm treatment rheumatology neurology symptoms anemia blood checklist workup acquired activation acute anesthesia anesthesiology ards arrhythmias arteritis ascites
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Sepsis • Drugs (e.g ... • Gilbert's Syndrome ... Crigler-Najjar Syndromes ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... Differential #Diagnosis #Causes ... #hematology #secondary
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
cardiac syncope, e.g ... carotid sinus syndrome ... further guide management ... orthostatic vital sign ... and an initial ECG
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Surgical devices, e.g ... Sepsis (→ 3-14) e.g ... (e.g. haloperidol ... hyperthermia crisis (late sign ... Checklist #Diagnosis #Management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Hepatorenal Syndrome ... nephrotoxics (e.g ... - No other cause ... - No other cause ... HRSAKI #HRSNAKI #hepatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
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