12 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... activation and cell ... can also mediate ADCC ... Hypersensitivity #Types #Classification ... #Pathophysiology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... Low Grade - Slow growing ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Thrombocytosis: cells ... tourniquet while drawing ... 7) - principal cells ... #causes #potassium ... #high #pathophysiology
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Clinical Classification ... disease Systolic dysfunction ... Diastolic dysfunction ... Langerhans cell ... #Differential #Causes
Shock Classification Types - Pathophysiology Comparison

Obstructive Shock:
 • Obstructive shock is characterized by a blockage in
Shock Classification ... Types - Pathophysiology ... in blood flow caused ... Depends on the cause ... Pulmonary embolism
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... : 1) T-cell dysfunction ... and increased B-cell ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... • Induce blast cell ... Imaging: CXR- pulmonary ... severe APLS, organ dysfuxtion ... fluid overload, PCC
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... smooth muscle cells ... gastrointestinal osmotic gradient ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
accumulates in cells ... essential for cell ... Glycosylation - AGE cause ... increasing cytogenetic dysfunction ... #DiabeticFoot #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
increases out of cells ... Vaughan Williams Classification ... ++ influx into cells ... #Pharmacology #Classification ... #Classes #pathophysiology