10 results
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... • Pathophysiology ... #Reactions #hematology ... #diagnosis #comparison ... #table
When assessing a patient with acute dyspnea during or shortly following a transfusion, it is challenging
shortly following a transfusion ... challenging to differentiate ... anaphylaxis, because all ... #TRALI #TACO #Comparison ... #Table
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Diuretics, PRBC transfusion ... have fever - ACS ... : • Pathophysiology ... diagnosis #management #hematology
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... anaphylaxis, release syndrome ... uw_IMresidency #Shock #Differential ... #Diagnosis #table ... #comparison #criticalcare
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... multiple myeloma or AL ... seen after blood transfusion ... #Diagnosis #comparison ... #table #dermatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... Grey Platelet Syndrome ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... ATRA treatment Pathophysiology ... initiation • Differential ... Differentiation #Syndrome
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... • Nephrotic Syndrome ... considered in all ... Venous #Arterial #pathophysiology ... #hematology #differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Encephalopathy Syndrome ... emergency, Blood transfusion ... Etiology: • Pathophysiology ... circulation: MCA ACA ... Reversible course Differential
Hyperthermic Toxidromes
Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures.
 • Sympathomimetic -
of muscarinic Ach ... • Serotonin Syndrome ... Hyperthermic #Toxidromes #comparison ... #table #diagnosis ... #differential #