14 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... e.g. lupus, CLL, lymphoma ... , idiopathic) ... Extravascular #Causes #differential ... #anemia
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 • Bacterial: Mycobacterium
Pericardial Effusion - Differential ... Non-Infectious: • Rheumatologic ... Malignant - Primary: Lymphoma ... • Metabolic: Uremia ... , Dissection, Idiopathic
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Disease (CAD): - Idiopathic ... Agglutinin Syndrome ... autoimmune disorder or lymphoid ... - Monoclonal - Lymphoid ... younger pts) Differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... Kawasaki, Nephrotic syndrome
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Dyspnea - Differential ... failure - CAD/ACS ... - Asthma - COPD ... Hepatopulmonary syndrome ... : - Anemia
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Anticonvulsants - Gold ... - Radiation • Idiopathic ... Treatment: ... #oncology #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... Treatment • Early
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Cell Leukemia • Idiopathic ... Significance (ICUS) • Idiopathic ... factor (GCSF) treatments ... blood count with differential ... #diagnosis #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Marginal Zone Lymphoma ... Marginal zone lymphoma ... (-) hemolytic anemia ... due to cold IgG ... #Monoclonal #Differential
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
Idiopathic CD4 Lymphopenia ... chemotherapy) • Genetic syndromes ... Unc119) • Heme (lymphoma ... #diagnosis #hematology ... #Differential #