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diagnosis hematology management algorithm allergy behcet cancer causes cll differentiation disease emergencies eosinophilia erythematosus hemeonc hodgkins hyperviscosity lupus lymphocytic lymphoma
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... Chronic leukemia ... Score • CML -> AML ... • Tumor lysis syndrome ... #Hematology #Oncology
Hyperviscosity Syndrome - Causes and Treatment - Waldenstrom macroglobulinemia (most common) / Plasmapheresis - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... Hydroxyurea - Leukemia ... hyperleukocytosis (AML ... #Causes #Differential
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... lymphoma & Acute leukemia ... (both ALL and AML ... malignancies Treatments ... #TLS #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... microglobulin Treatment ... #CLL #Chronic ... diagnosis #workup #oncology ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Incidence: common in APL ... initiation • Differential ... #oncology
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Eosinophilia - Differential ... • Eosinophilic Leukemia ... ), Heme malig (AML ... insufficiency, Chronic ... #Eosinophilia #Differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... Marrow Failure • Chronic ... blood count with differential ... progression to AML ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Usually myeloid leukemias ... → no immediate treatment ... : - Seen with AML ... (~20 %) and APL
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... involved) • No leukemic ... #oncology #diagnosis ... #differential # ... hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behcet disease) Differential ... tears, Ischemia, Leukemia ... Arthritis, AS Treatment ... Recurrent and chronic ... signs #symptoms #rheumatology
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