10 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Features: POEMS, AL ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology ... #oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Patients with Cancer ... Cancer Related ... tubulopathy • Monoclonal ... malignancies Treatment ... #Oncology #Differential
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Score • CML -> AML ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... #Oncology #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Incidence: common in APL ... initiation • Differential ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... Evans • ITP • Cl-NH ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... blood count with differential ... progression to AML ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... microglobulin Treatment ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Causes of Monoclonal ... changes (POEMS syndrome ... Castleman disease • AL ... ovarian tumors, lung cancers ... Gap #ProteinGap #differential
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... current treatment ... Myelodysplastic syndromes ... myeloid leukemia (AML ... cytopenias and AML