19 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
permeability Diagnosis ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis ... #management #treatment
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
): • Lupus anticoagulant ... Anticardiolipin antibodies (aCL ... to be present Treatment ... #management #anticoagulation ... #guidelines
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
- Follow local guidelines ... splenomegaly, abnormal neurology ... cell disease Rheumatology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... hemopathies, solid cancers ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... center. ... Avoid meds that ... #Management #treatment ... #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Autoimmune disease, Cancer ... circulation: MCA ACA ... epilepticus Treatment ... #management #neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... #management #hematology
Pulmonary Nodule
Evaluation is guided by nodule size & assessment of probability of malignancy. In addition is
yield of available diagnostic ... The treatment of ... Management options ... 70% to 90% for a diagnosis ... of lung cancer.
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... cardiomyopathy • Pulmonary ... e.g., <50%), ESC guidelines ... teratogenic GDMT meds ... #treatment