11 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
function test, ANA (e.g ... (CVID, WAS), (neurologic ... not required in all ... or if a primary hematologic ... #Workup #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... have fever - ACS ... unless worrisome EKG ... diagnosis #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Pisa Syndrome (pleurothotonus ... Caused commonly ... Pathophysiology: ... PhysicalExam #clinical #neurology ... #posture #video
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
• Nephrotic Syndrome ... considered in all ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... ATRA treatment Pathophysiology ... Prednisone 5mg/kg ... diagnosis #management #hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... complete paralysis of all ... Electrodiagnostic studies - EMG ... management #treatment #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... circulation: MCA ACA ... the underlying cause ... with AEDs until cause
Orbital Apex Syndrome secondary to Herpes Zoster Ophthalmicus (HZO)

This 81 yo male was referred to our
reported this all ... other potential causes ... acyclovir 10mg/kg ... HZO #clinical #video ... #physicalexam #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... the underlying pathophysiology ... Guillain #Barre #Syndrome ... diagnosis #management #neurology