54 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome ... Constipation • Nausea
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... Myelodysplastic #Syndrome ... Management #treatment #hematology ... #oncology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
Cardiovascular Causes ... failure - CAD/ACS ... Hepatopulmonary syndrome ... Other Causes ... Transverse myelitis • Hematology
Chest Pain - Differential Diagnosis Framework

Cardiovascular Causes of Chest Pain:
 • Myocardium:
	- Myocarditis
	- CAD/ACS
	- Valvulopathy
	- Myopericarditis
Cardiovascular Causes ... Myocarditis - CAD/ACS ... Tamponade Pulmonary Causes ... Costochondritis - Tietze syndrome ... #Cardiology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Tree in Bud Sign
The Tree-in-Bud sign represents Endobronchial spread in a linear branching pattern and centrilobular
It is caused by ... actually seen in all ... causes of infective ... diagnosis #clinical #radiology ... #ChestCT #pathophysiology
Wolff–Parkinson–White syndrome (WPW) is one of several disorders of the electrical system of the heart that
Wolff–Parkinson–White syndrome ... pre-excitation syndromes ... WPW is caused by ... #Pathophysiology ... #Diagnosis #Cardiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... have fever - ACS ... : • Pathophysiology ... diagnosis #management #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... ATRA treatment Pathophysiology ... diagnosis #management #hematology ... #oncology