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hyperkalemia management nephrology differential algorithm causes syndrome achalasia binder criticalcare crystalloids diuresis diuretics druginduced emergencies encephalopathy excretion foamed gastroenterology guidelines
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... Increased EC shift of K ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Differential Diagnosis ... phlebotomy High ... • NSAIDs • ACE ... Beta blockers • Antibiotics ... Medications 2.
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
- Differential Diagnosis ... phlebotomy High ... • NSAIDs • ACE ... Beta blockers • Antibiotics ... Medications 2.
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... NSAIDs, β-blockers, Antibiotics ... STOP offending medications ... Ca-gluconate or 1g CaCl ... #potassium #nephrology
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
depletion • Consider K+ ... Dialysis Serum potassium ... and ECG changes ... #high #diagnosis ... management #algorithm #treatment
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
) MECHANISM: Potassium ... INDICATION: Treatment ... needed, based on K ... ACE inhibitors, ... #Hyperkalemia #Pharmacology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... have fever - ACS ... Spontaneous if high ... values: Elevated K, ... Syndrome #TLS #diagnosis
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome • Diagnosis ... Diuretics; High-Ceiling ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
The crusade against “Ab”Normal Saline continues. This is a non-physiologic fluid that can harm our
is dominated by K+ ... we introduce a high ... The high CL- content ... criticalcare #management #diagnosis ... #treatment #pharmacology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Syndrome (PRES) Overview ... circulation: MCA ACA ... Electrolyte abnormality, Medication ... epilepticus Treatment ... underlying cause • Treatment
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