43 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #management #algorithm
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... hyperleukocytosis (AML ... #Causes #Differential ... #Diagnosis #Treatment ... #Management
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
- Diagnosis and ... Management • ... #Diagnosis #Management ... #treatment #hematology ... #differential
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... Anticardiolipin antibodies (aCL ... at least: • 1 clinical ... to be present Treatment ... #management #anticoagulation
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... #management #hematology
REBEL Review 99: Serotonin Syndrome via Yosuf Alam, MSIV

Presentation: Altered mentd status, Seizures, Myoclonus, Hypertension, Hyperthermia
99: Serotonin Syndrome ... : Clinical! ... Cornerstone of treatment ... discontinuing all ... SerotoninSyndrome #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
have fever - ACS ... organ damage • Treatment ... Low calcium • Treatment ... #TLS #diagnosis ... #management #hematology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Clinical ... • Weakness: Starts ... Guillain-Barre Diagnosis ... #diagnosis #management ... #treatment #neurology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Features: POEMS, AL ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... life-threatening Differential ... myasthenia Diagnosis ... Myasthenia #Gravis #diagnosis ... #management #neurology