5 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Supportive Care: Diuresis ... #management #hematology ... #oncology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Inhibitors of Na+K+2Cl ... Kidney stones caused ... Tolvaptan) • Treatment ... #Nephrology #Pharmacology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... that are poorly formed ... transformation to AML ... progression to AML ... diagnosis #hematology #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... Treat underlying cause ... Adjuncts: loop diuretics ... : - Seen with AML ... (~20 %) and APL
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
excreted using diuretics ... acute coronary syndrome ... the determined cause ... #table #foamed ... heartfailure #chf #criticalcare