26 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... Hemolysis, Elevated Liver ... tests, Low Platelets ... exchange 3) Fatty liver ... coagulation defects and liver
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Hemolysis, Elevated Liver ... tests, Low Platelets ... exchange 2) Fatty liver ... coagulation defects and liver
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... History: - Prior platelet ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... Causes #Workup #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... count and platelet ... measuring vWF level ... Gplb receptor • Thrombcytopenia ... #disorders #hematology
Algorithm for the outpatient management of thrombocytopenia. 
(DIC = disseminated intravascular coagulation; EDTA = ethylenediaminetetraacetic acid;
management of thrombocytopenia ... hemolysis, elevated liver ... enzymes, and low platelet ... ; ITP = immune thrombocytopenic ... TTP = thrombotic thrombocytopenic
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Diagnosis Algorithm Thrombocytopenia ... Sequestration Disordered Platelet ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
inflammation • Thrombocytopenia ... • Platelet defects ... Primary Causes: - Thrombocytopenia ... deficiency • Liver ... #nonpalpable #dermatology
Spider Angioma: Dialated superficial arterioles, most commonly associated with advanced liver disease.

Charlie Goldberg, M.D. - UCSD
with advanced liver ... Images #Clinical #Photo ... #Dermatology #Rash
Platelet Disorders - Differential Diagnosis Framework

Qualitative Defects:
 • Adhesion
 • Aggregation
 • Secretion

Quantitative Defects:
 • Production:
Platelet Disorders ... • Production: Liver ... ASanchez_PS #Platelet ... Differential #Diagnosis #hematology ... #thrombocytopenia
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Hemolysis, Elevated Liver ... enzymes, and Low Platelets ... clinical features: Liver ... BrighamChiefs #Liver