9 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding Agents ... and sodium • Dosing ... 10 g QD (adjust dose ... Usual maintenance dose ... g QD; increase dose
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
maximum daily dose ... phosphate binding agents ... Generally, the initial dose ... restricted due to hypercalcemia ... #Dosing #Pharmacology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Hyponatremia - Differential ... Diagnosis Algorithm ... deficiency, Salt-losing ... renal failure Hypervolemia ... #Diagnosis #Algorithm
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... Treatment Algorithm ... -2 hours Dose ... ~2 hours Dose ... removal of offending agent
Diarrhea Workup and Management Algorithm in Transplant Patients
First Tier Microbiologic-Testing:
1. C. difficile PCR (Stool)
2. CMV qPCR
and Management Algorithm ... medications *Reduce dose ... change to different agent ... anti-motility agents ... Transplant #diagnosis #differential
Eczematous Skin Rash - Differential Diagnosis Algorithm
Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated
 • Atopic Dermatitis
Eczematous Skin Rash - Differential ... Diagnosis Algorithm ... requires high doses ... of the agent. ... #Diagnosis #Algorithm
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... use of adequate doses ... antihypertensive agents ... disorders including hypokalemia ... Workup #causes #Differential
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic Emergencies ... incontinence - High-dose ... plasmapheresis Hypercalcemia ... differentiating agent ... #Oncologic #Emergencies
Pragmatic diagnostic algorithm for hypokalemia. 
***Typical presentations: 
 • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic algorithm ... for hypokalemia ... severe to the dose ... #diagnosis #differential ... #algorithm #nephrology