21 results
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
most often in 2nd trimester ... TTPHUS #HELLP #AFLP ... #Obstetrics #OBGyn ... #Hematology #Diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Typically 3rd trimester ... iMedEducation #AFLP ... Liver #Pregnancy #hepatology ... #obstetrics #obgyn
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... Algorithm for Transaminitis ... Wilsons, Pregnancy - AFLP ... Transaminitis #Algorithm ... #diagnosis #hepatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
of Pregnancy (AFLP ... most often in 2nd trimester ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... #diagnosis #table
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
ICP) • Onset/Trimester ... of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... #differential #diagnosis ... #icp #HELLP #AFLP
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
transaminits #pregnancy #obgyn ... #obstetrics #hepatology ... #diagnosis #differential ... #algorithm
Antenatal / Prenatal Care Schedule 
At Every Visit: Weight, Blood pressure, Psychosocial screening, Counseling re. Indications
of delivery • Dating ... serum screen (AFP ... • ± Prenatal diagnosis ... Care #Schedule #Diagnosis ... Evaluation #Obstetrics #OBGyn
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Algorithm Severe ... • Pregnancy - AFLP ... Others #LFTs #Hepatology ... #Algorithm #Causes
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Algorithm Peripheral ... → Refer to hematology ... myelosuppressive agents ... #Algorithm #hematology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... - Increased ALP ... #Differential #Diagnosis ... #Algorithm #hepatology