400 results
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Thiazide Type - Loop ... Blocker - Carbonic Anhydrase
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Acetazolamide (carbonic anhydrase ... . mannitol) 3) Loop
Overview of effects of diuretics and hormones involved in fluid homeostasis.

#diruetic #diuretics 
#aldosterone #ADH #ANP #BNP
#thiazide
hydrocholorothyazide #loop ... amiloride #carbonic #anhydrase
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Interaction CARBONIC ANHYDRASE ... empagliflozin LOOP
Thiazide
diuretics
Carbonic anhydrase
inhibitors
(e.g., acetazolamide)
Nat-Cl symport
Na and HCO;-
reabsorption
Aldosterone
antagonists
(e.g., spironolactone)
Nat channel
(indirect effect)
Loop diuretics (e.g., furosemide)
Amiloride,
#triamterene
Nat-K+-2CF symport
Na channel
(direct effect)
#NaCI reabsorption
diuretics Carbonic anhydrase ... indirect effect) Loop
Internal Jugular Vein Rouleaux Flow on POCUS

Amazing video of a dilated IJV showing Rouleaux flow. Whenever
Rouleaux Flow on POCUS ... significantly, it causes ... Always look for ... underlying cause ... Jugular #IJ #Vein #POCUS
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... Triamterene Carbonic anhydrase ... nephrology #conversion #loop ... #thiazide #classes
Approach to determining the cause of a blood clot
1) Is it acquired?
2) Should you consider inheritable
determining the cause ... consider inheritable causes ... 3) Should you look ... VTE #diagnosis #causes
Causes of Non-Gap Metabolic Acidosis - Differential Diagnosis Algorithm
Normal Anion Gap (<14) (Loss of Bicarbonate) -
Causes of Non-Gap ... II • Carbonic anhydrase ... Diagnosis #Algorithm #Causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause ... Clinicians should also look ... diagnosis #algorithm #causes