9 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... LAC) • Sjogren Syndrome ... • Scleroderma (Systemic ... diagnosis #associations ... #table
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... the formation of autoantibodies ... permeability Diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
neuropathy) • Systemic ... macular Vasculitis) Autoantibodies ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
-15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... #Antinuclear #autoantibodies ... erythematosus #diagnosis ... table #ANA
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
Diagnosis of IgA ... 1) Suggestive clinical ... - Most common systemic ... #Rheumatology # ... Peds #Pediatrics
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... • Anti-Ro/SSA autoantibodies ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Clinical Features
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... months) and of autoantibodies ... months to years) Systemic ... sle #comparison #table ... diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... the lymphatic system ... renal failure Clinical ... papules, nodules; anterior ... 5-10%, nervous system
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... • Presence of systemic ... Marfan syndrome, ... Disorders #History #peds ... #pediatrics #diagnosis